You are not alone! I am also having the same problem, and I am also using windows 10.Maybe... I have a win7 laptop, I'll give that a try.
It's weird, the RC Assistant software loads, but doesn't see the TX when I plug it in and turn it on. The Phantom Assistant software seems to work just fine, but the RC Assistant does not.
Thanks for confirming I'm not alone.
Having the same problem with Windoze 10. RC Assistant doesn't see the controller.
Anybody find a fix for this? I'm using DJI WIN driver V2.02.
P2V+. Old model controller.
Phantom Assistant sees the bird ok.