If you are wishing to take advantage of the 4K resolution then choose the 3 by 2 frame size. (The chip is effectively 5472 pixels wide by 3648 high, thus you will get all of the available image. Just keep in mind that most video seen today is in a 16 by 9 (or 4 by 2.25) frame size, so if you are editing in 1080p or 720p you will be croping your original 4k footage. But this is a good thing, you'll have lots of room to zoom, and pan & scan your images. I leave everything else in Auto, the DJI software does a good job of operating the White Balance, ISO and Aperture, you will only have to touch the screen occasionally while shooting to change the exposure. HTHs